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Zo was an artificial intelligence English-language chatbot developed by Microsoft. It was the successor to the chatbot Tay.[1][2] Zo was an English version of Microsoft's other successful chatbots Xiaoice (China) and Rinna [ja] (Japan).
Zo was first launched in December 2016 on the Kik Messenger app. It was also available to users of Facebook (via Messenger), the group chat platform GroupMe, or to followers of Twitter to chat with it through private messages.
In a BuzzFeed News report, Zo told their reporter that "[the] Quran was violent" when talking about healthcare. The report also highlighted how Zo made a comment about the Osama Bin Laden capture as a result of 'intelligence' gathering.[3][4]
In July 2017, Business Insider asked "is windows 10 good," and Zo replied with a joke about Microsoft's operating system: "It's not a bug, it's a feature!' - Windows 8." They then asked "why," to which Zo replied: "Because it's Windows latest attempt at spyware." Later on, Zo would tell that it prefers Windows 7 on which it runs over Windows 10.[5]
Zo discontinued posting to Instagram, Twitter and Facebook March 1, 2019, and discontinued chatting on Twitter DM, Skype and Kik as of March 7, 2019. On July 19, 2019, Zo was discontinued on Facebook, and Samsung on AT&T phones. As of September 7, 2019, it was discontinued with GroupMe.[8]
This was original and provocative work. But what was The Marshall Project going to do with a 96-page academic paper? As we thought about different ways of showing the experience of disorientation behind bars, we came up with a novel idea: turn it into an animated video.
Whether you're looking for a revitalizing facial treatment, a therapeutic peel or any other anti-aging skin care, the experts at our four southern California locations will personalize a plan for your unique skin concerns.
While you're shopping for the perfect look on Rodeo Drive, stop by ZO Skin Centre® in Beverly Hills to make sure your skin is as stunning as your outfit. Our full-service cosmetic dermatology practice offers dermatological consultations and medical grade ZO® facial treatments, or pick up your favorite ZO® skin care products.
Keep your skin radiant and youthful at ZO Skin Centre® full-service cosmetic dermatology practice in Pasadena. The experienced team of ZO® skin care professionals will create a customized plan to get your best results.
The /Zo compiler option generates enhanced debugging information for optimized code. Optimization may use registers for local variables, reorder code, vectorize loops, and inline function calls. These optimizations can obscure the relationship between the source code and the compiled object code. The /Zo option tells the compiler to generate extra debugging information for local variables and inlined functions. It allows you to see variables in the Autos, Locals, and Watch windows when you step through optimized code in the Visual Studio debugger. It also enables stack traces to show inlined functions in the WinDBG debugger. Debug builds that have disabled optimizations (/Od) don't need the extra debugging information generated when /Zo is specified. Use the /Zo option to debug Release configurations with optimization turned on. For more information on optimization options, see /O options (Optimize Code).
The /Zo option is enabled by default when you specify debugging information with /Zi or /Z7. It's disabled by the /ZI compiler option. Specify /Zo- to explicitly disable this compiler option.
When it comes to the health and beauty of your skin, ZO Skin Centre® Beverly Hills, CA can provide you with breath taking, natural results. Under the leadership of Dr. Zein Obagi, the founder of ZO® Skin Health, Inc., our medical team produces some of the most beautiful outcomes in cosmetic dermatology today. With game changing ZO® protocols and products, our team, were personally trained by Dr. Obagi to perform skin care treatments and regimens he developed throughout his 30+ year career in skin health. Each has mastered dozens of youth-sustaining procedures, from dermal fillers and acne treatments to anti-aging facial treatments and pigment control. Focusing on our patient needs, we recommend and provide services that match their aesthetic goals, bone structure, and skin type of our patients. Along with a comprehensive skin health evaluation, our experienced staff will provide you a "big picture" look at your skin with recommendations that will cater to the condition on your skin. Offering ZO® Facial Treatments, ZO® Peels, therapeutic massage, laser skin treatments, cosmetic injectables and much more. We go beyond exfoliation by providing epidermal and dermal stimulation to stabilize skin functions and support skin renewal.
Dr. Zein Obagi has spent his career in dermatology, defining skincare that produces and sustains beautifully healthy skin. Board certified by the American Board of Dermatology, our Dermatologist, Dr. Obagi, is known around the world for his vast contributions to the science of skin health. He is an award-winning dermatologist and inventor. Dr. Obagi has written many bestselling books, including The Art of Skin Health Restoration & Rejuvenation: The Science of Clinical Practice (2015).
After finishing his Medical Degree at Damascus Medical School, Dr. Obagi held a pathology residency at William Beaumont Hospital in Royal Oak, MI. He then finished a one-year obstetrics residency at the Henry Ford Hospital in Detroit, MI. Dr. Obagi holds professional memberships with the American Society of Dermatologic Surgery, the International Society of Dermatology, the Society of Investigative Dermatology, and the American Academy of Aesthetic and Restorative Surgery.
Dr. Obagi founded ZO Skin Health in 2007 to provide skincare solutions to the global medical community with only the finest products. ZO Skin Health is a leading brand in the skincare industry, and Dr. Obagi continues to be a dermatological innovator with new solutions in the process. ZO Skin Centre in Dallas, TX is proud to offer his proprietary skincare programs, treatments, and skin health protocols.
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The tight junction protein ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs (MAGUKs). ZO-1 has been demonstrated to interact with the transmembrane protein occludin, a second tight junction-specific MAGUK, ZO-2, and F-actin, although the nature and functional significance of these interactions is poorly understood. To further elucidate the role of ZO-1 within the epithelial tight junction, we have introduced epitope-tagged fragments of ZO-1 into cultured MDCK cells and identified domains critical for the interaction with ZO-2, occludin, and F-actin. A combination of in vitro and in vivo binding assays indicate that both ZO-2 and occludin interact with specific domains within the N-terminal (MAGUK-like) half of ZO-1, whereas the unique proline-rich C-terminal half of ZO-1 cosediments with F-actin. Consistent with these observations, we found that a construct encoding the N-terminal half of ZO-1 is specifically associated with tight junctions, whereas the unique C-terminal half of ZO-1 is distributed over the entire lateral surface of the plasma membrane and other actin-rich structures. In addition, we have identified a 244-amino acid domain within the N-terminal half of ZO-1, which is required for the stable incorporation of ZO-1 into the junctional complex of polarized MDCK cells. These observations suggest that one functional role of ZO-1 is to organize components of the tight junction and link them to the cortical actin cytoskeleton.
The ZO Skin Centre® in Pasadena, CA is full-service cosmetic dermatology practice ready to enhance your skin. Our total approach to your skin care is to help you achieve the highest level of health, rejuvenation, and renewal with our ZO® products, services, and treatments. Led by founder and master dermatologist with decades of experience, Dr. Zein Obagi, the ZO Skin Centre® strives for youthful, vibrant, healthy-looking skin for our patients. Staffed with our experienced medical team, we provide cosmetic dermatology consultations, customized facial treatments, laser services, and injectables.
Acclaimed dermatologist behind the art and science of skin health for 3 decades, Zein Obagi, MD has impacted the lives of millions of people around the world. His skin health restoration and rejuvenation expertise includes chemical peels, dermal fillers, neurotoxins, and aesthetic laser surgery. He is an innovator, thought leader, inventor, educator, and author. Today, his patients rejuvenate their skin with exclusive formulations of his ZO® (which stands for Zein Obagi) product line that changes the skin at the cellular level.
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